Testing Cardiovascular Drug Safety and Efficacy in Randomized Trials
نویسندگان
چکیده
منابع مشابه
Testing cardiovascular drug safety and efficacy in randomized trials.
Randomized trials provide the gold standard evidence on which rests the decision to approve novel therapeutics for clinical use. They are large and expensive and provide average but unbiased estimates of efficacy and risk. Concern has been expressed about how unrepresentative populations and conditions that pertain in randomized trials might be of the real world, including concerns about the ho...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.301809